Age is the strongest single predictor of IUI success. Use this calculator for a quick age-based estimate per cycle and across three tries, then open Advanced to reflect meds, sperm, follicles and timing.
Success rates by age
Below are estimated IUI success rates per cycle and across 3 cycles. These figures are drawn from published studies and clinic data. Rates vary depending on stimulation protocols and patient factors.
- Age 20–24: ~15–20% per cycle, up to 40–50% within 3 cycles
- Age 25–29: ~12–18% per cycle, up to 35–45% within 3 cycles
- Age 30–34: ~10–15% per cycle, up to 30–40% within 3 cycles
- Age 35–37: ~8–12% per cycle, up to 25–30% within 3 cycles
- Age 38–40: ~5–8% per cycle, up to 15–20% within 3 cycles
- Age 41–42: ~3–5% per cycle, up to 10–12% within 3 cycles
- Age 43+: <2% per cycle, limited cumulative benefit
Sources: ASRM, HFEA, Fertility & Sterility journal.
What changes your odds beyond age
Several factors influence whether IUI will be successful:
- Ovarian reserve: AMH, FSH, and antral follicle counts help predict egg supply.
- Sperm parameters: Motility and morphology strongly affect outcomes.
- Stimulation protocol: Using ovulation medications typically raises success rates compared to natural cycles.
- Timing: Precise alignment of insemination with ovulation is critical.
- Cycle number: Most pregnancies occur within the first 3–4 attempts.
See the Advanced calculator to model these factors in more detail.
When to consider IVF instead of IUI
Clinics often set age-based thresholds for when to try IVF rather than multiple IUI cycles:
- Under 35: Up to 3–6 IUI cycles may be reasonable before IVF.
- Ages 35–37: Consider IVF if IUI has not worked after 3–4 cycles.
- Ages 38–40: Some clinics move directly to IVF due to lower IUI success rates.
- Over 40: IVF is generally recommended first-line.
Sources: ASRM guidelines, fertility clinic protocols.
Frequently asked questions
Is IUI effective after 40?
Success rates drop significantly after 40, often below 5% per cycle. Most clinics recommend IVF instead.
How many IUI cycles should I try at my age?
Many pregnancies occur in the first 3–4 cycles. Beyond that, cumulative benefit declines.
Does medication improve IUI success at older ages?
Yes, stimulation medications can raise success rates, but age-related decline still dominates outcomes.
Does male age matter for IUI?
Male age has a smaller effect than female age but can reduce success if sperm parameters are impaired.