AMH Levels by Age: Interpreter

What this shows

The tool places a user’s anti-Müllerian hormone (AMH) result in an age-adjusted context. It reports an approximate percentile for age, a descriptive band (low, typical, high), a unit conversion between ng/mL and pmol/L, and a plain-language note on interpretation limits. If dated prior results are entered, it estimates a simple trend. It also shows an educational IVF egg yield band derived from AMH only.

Modelling approach

• Age model: AMH declines with age and is right-skewed, so a log-normal shape is used for percentiles. The median by age is set with a stylised step function that follows common population patterns. Dispersion is held constant (sigma ≈ 0.45) to map a user value to a cumulative probability and percentile.
• Bands: below the 10th percentile is labelled low for age, above the 90th percentile high for age, values in between are within typical range for age.
• Units: results are accepted in ng/mL or pmol/L. A common cross-assay factor of 1 ng/mL ≈ 7.14 pmol/L is used for conversion. Assay-specific factors vary, so the conversion is approximate.
• Lab range echo: if a lab range is entered, the tool displays it with the selected unit and indicates whether the current value sits below, within, or above that range.
• Trend: when at least two dated AMH values are provided, the tool computes the percentage change per year between the oldest and newest points and classifies it as rising, falling, or roughly stable.
• IVF egg yield band: an educational mapping from AMH (ng/mL) to expected mature oocytes in a standard stimulation is displayed as broad bands only. This varies by protocol, clinic, and response, so it is not a prediction.

Clinical context and caveats

• AMH reflects estimated ovarian reserve. It does not predict natural fecundability in a given month and it does not diagnose infertility on its own.
• Cycle day has minimal effect for most assays, so many labs draw on any day.
• Hormonal contraception can lower measured AMH in some users and some assays. Recent discontinuation can also affect values.
• High AMH can be consistent with polycystic ovary syndrome when clinical criteria are present. AMH alone is not diagnostic.
• Assay methods differ across laboratories. Reference intervals are not interchangeable. Use the lab’s own range when available.

Limitations

Percentiles are modelled for education and are not a substitute for laboratory reference intervals or clinician interpretation. The conversion factor between ng/mL and pmol/L is approximate and assay dependent. The egg yield band is illustrative and does not account for dose, stimulation protocol, antral follicle count, or clinic-level outcomes.

Sources

• American Society for Reproductive Medicine, Committee Opinion, “Testing and interpreting measures of ovarian reserve.”
• ESHRE Guideline on ovarian stimulation for IVF, background on AMH and oocyte yield relationships.
• NICE Guideline CG156, “Fertility problems: assessment and treatment,” ovarian reserve testing context.
• Studies on AMH and combined oral contraception that report reduced measured AMH during use and after recent discontinuation.
• Manufacturer and large lab documentation for AMH unit conversions noting assay-specific factors and common 7.14 multiplier.