How to use this euploid embryo calculator
- Enter your AMH level in ng/mL (e.g., 2.4).
- Enter your age in years.
- Click Calculate to see:
- Chance of at least one euploid embryo from a stimulation cycle
- a short note on how your AMH compares with an age-specific anchor (“T50”)
Guardrails: the current model supports ages ~29–44 years. Very low/high AMH values may trigger warnings.
Methodology & sources
What this tool estimates
- A single probability that a stimulation cycle produces at least one euploid embryo, using age and AMH as inputs.
- This is not a prediction of pregnancy, implantation, or live birth.
Inputs
- Age (years): accepted range 29 to 44. Outside this range, the estimate is not shown.
- AMH (ng/mL): must be a number 0 or higher. Non-numeric entries are blocked.
How the estimate is built
- Age-specific AMH reference: the calculation uses the AMH values in Dr. Lucky Sekhon’s published predictor table for ages 29–44. Each value marks a 50% estimate in that predictor.
- Your estimate: a smooth curve compares your AMH with the reference for your age, then applies an age adjustment. The displayed percentage can therefore differ from 50% at the reference value.
- Outcome: the result estimates the chance of at least one euploid embryo from a stimulation cycle. It does not calculate an egg count, a separate per-embryo rate, or a live-birth chance.
- Range: the percentage is kept between 0 and 100%. Higher AMH generally reflects greater ovarian response, not better chromosome quality.
Output & display rules
- Primary output: "Chance of at least 1 euploid embryo" rounded to 1 decimal place (with a <0.1% floor label for very small values).
- Status text: echoes the age and AMH used to compute the estimate.
Assumptions & limitations
- AMH helps estimate likely response (how many eggs), but it does not measure egg or embryo genetic health. Age remains the strongest driver of aneuploidy patterns.
- Real outcomes vary with stimulation protocol, lab conditions, fertilisation method, embryo culture, and patient factors not captured here.
- PGT-A has technical limits, including mosaic results and false calls. This tool does not model those testing limits.
Sources
- Franasiak JM, Forman EJ, Hong KH, et al. The nature of aneuploidy with increasing age of the female partner. Fertil Steril. 2014;101(3):656-663.e1. doi:10.1016/j.fertnstert.2013.11.004.
- Cedars MI. Evaluation of Female Fertility - AMH and Ovarian Reserve Testing. J Clin Endocrinol Metab. 2022;107(6):1510-1519. doi:10.1210/clinem/dgac039.
- Endotext (NCBI Bookshelf). Ovarian Reserve Testing. Updated review chapter discussing AMH/AFC for predicting ovarian response.
- Practice Committees of ASRM and SART. The use of preimplantation genetic testing for aneuploidy (PGT-A): a committee opinion. Fertil Steril. 2018;109(3):429-436. doi:10.1016/j.fertnstert.2018.01.002.
- Nair J, Shetty S, et al. Preimplantation genetic testing for aneuploidy (PGT-A) - a single-center experience. J Assist Reprod Genet. 2022. (Open access; includes age-related aneuploidy patterns.)
Understanding your results
Chance of ≥1 euploid embryo
This answers: “If we retrieve and culture expected embryos, what’s the probability that at least one is chromosomally normal (euploid)?”
Age and embryo chromosomes
Age helps put the estimate in context because the proportion of embryos with chromosome abnormalities generally rises with age.
AMH and ovarian response
AMH gives information about likely ovarian response. The result combines age and AMH into one cycle-level probability; your clinic can estimate egg and embryo numbers for your treatment.
Important context
- Quality vs quantity: AMH tracks egg quantity, not chromosome quality.
- Clinic & protocol factors: Stimulation approach, lab variability, and day-3 vs day-5 culture can shift actual outcomes.
- PGT-A: Genetic testing reports embryo ploidy directly; this calculator provides a planning-stage estimate only.
Euploid probability: FAQs
Does AMH measure embryo quality?
No. AMH reflects egg supply, not chromosomal quality. Age is the dominant driver of euploidy. For AMH ranges and interpretation, see the AMH levels by age tool.
How accurate is this calculator?
It’s a planning-stage estimate using age-specific AMH reference values and a smooth probability curve. Real outcomes vary by stimulation protocol, lab performance, and individual biology. PGT-A is the only way to determine embryo ploidy directly.
How many eggs do I need for one euploid embryo?
The number varies with age and how many eggs develop into blastocysts. This calculator gives a cycle-level chance; your clinic can estimate egg and embryo numbers for your treatment. If you’re family-building over time, you may also consider the egg freezing success rate tool for strategy.
Does day-3 vs day-5 culture change results?
Culture strategy affects how many embryos reach testing/transfer. The euploid rate is largely age-related, but the number of testable/transferable embryos can differ. For transfer considerations, see embryo grade success rate.
Can male factor change euploid probability?
Severe sperm DNA fragmentation or very low counts may impact embryo development. Use the semen analysis & TMSC interpreter for context and discuss with your clinic.
How does this relate to IVF success rates?
Euploid embryos generally have higher implantation potential. For age-stratified clinical outcomes, compare with the IVF success rate by age calculator.
This calculator uses age-specific AMH reference values and a smooth probability curve to produce a planning-stage estimate. It’s intended for education and shared decision-making—please discuss your individual plan and protocol with your clinician.