Euploid Embryo Probability Calculator (AMH + Age)

Estimate your chance of getting at least one euploid embryo from a retrieval using two inputs: AMH (ng/mL) and age. You’ll also see a per-embryo euploid rate and the model’s expected blastocyst count to help with IVF planning discussions.
Chance of ≥1 euploid embryo: —
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Educational estimate only; not medical advice.

What this tool estimates

  • A single probability that at least one embryo from a stimulation cycle will be euploid, based on the user’s age and AMH level.
  • A progress bar and readable percent label; no storage or analytics are used.

Inputs

  • Age (years): accepted range 29–44. Outside this range the model is not displayed.
  • AMH (ng/mL): nonnegative real number; simple input guards prevent nonnumeric entries.

Core model (how the number is computed)

  • Age-specific AMH anchor (T50): the tool keeps a small table of ages and the AMH that corresponds to about a fifty percent chance of at least one euploid embryo. For ages between listed points, the tool linearly interpolates the anchor.
  • Logistic transform of AMH vs. anchor: it computes
    z = slope × ln((AMH + ε) / (T50(age) + ε)), then converts with base = 1 / (1 + e−z). Constants: slope ≈ 0.70, small offset ε = 0.05 to stabilize very low AMH.
  • Gentle age-band correction: a small additive adjustment in percentage points is applied by age bands to better match typical counselling targets across the mid-30s to early-40s. The final probability is clamped to 0–100% and then re-scaled to 0–1.

Why a logistic form?

  • It maps very low AMH far below the age-specific anchor to a low probability, centers the curve near the anchor around fifty percent, and saturates near one hundred percent as AMH rises well above the anchor for that age.
  • It yields smooth, monotone responses that are easy to explain in counselling.

Output & display rules

  • Primary output: “Chance of ≥1 euploid embryo” rounded to one decimal place (with <0.1% floor label for very small values).
  • Status text: echoes the age, AMH, and the current T50 anchor used for that age.

Assumptions & guardrails

  • The estimate is for at least one euploid embryo across the cycle, not the per-embryo euploid rate.
  • No clinic-specific lab effects, stimulation protocols, or oocyte yield adjustments are modeled beyond the age-band correction embedded in the curve.
  • Out-of-range inputs are rejected. AMH below zero is coerced to zero. Probabilities are clamped to 0–100%.
Educational tool only. Real probabilities vary with ovarian response, embryo number and quality, lab conditions, and patient-specific factors. Use clinical judgement and local data where available.

Sources

  • Iliodromiti S, Jurema MW, Anderson RA, Nelson SM. Evaluation of Female Fertility—AMH and Ovarian Reserve Testing. J Clin Endocrinol Metab. 2022;107(6):1510–1526. Review summarizing how AMH relates to oocyte yield and expected embryo numbers. academic.oup.com/jcem/article/107/6/1510/6518212

Last updated: 16 Oct 2025

How to use

  1. Enter your AMH level in ng/mL (e.g., 2.4).
  2. Select your birthdate to determine age.
  3. Click Calculate to see:
    • Chance of ≥1 euploid embryo (main result)
    • Per-embryo euploid rate (age-based)
    • Expected blastocyst count (AMH-informed)

Guardrails: the current model supports ages ~29–44 years. Very low/high AMH values may trigger warnings.

Understanding your results

Chance of ≥1 euploid embryo

This answers: “If we retrieve and culture expected embryos, what’s the probability that at least one is chromosomally normal (euploid)?”

Per-embryo euploid rate

An age-based estimate of the proportion of embryos expected to be euploid. As maternal age rises, this percentage typically declines.

Expected blastocyst count

AMH helps approximate the number of embryos that may reach blastocyst stage after stimulation and culture. The tool combines this with your age to project a reasonable range.

Important context

  • Quality vs quantity: AMH tracks egg quantity, not chromosome quality.
  • Clinic & protocol factors: Stimulation approach, lab variability, and day-3 vs day-5 culture can shift actual outcomes.
  • PGT-A: Genetic testing reports embryo ploidy directly; this calculator provides a planning-stage estimate only.

Euploid probability: FAQs

Does AMH measure embryo quality?

No. AMH reflects egg supply, not chromosomal quality. Age is the dominant driver of euploidy. For AMH ranges and interpretation, see the AMH levels by age tool.

How accurate is this calculator?

It’s a planning-stage estimate using age-based euploid curves and an AMH-informed blastocyst expectation. Real outcomes vary by stimulation protocol, lab performance, and individual biology. PGT-A is the only way to determine embryo ploidy directly.

How many eggs do I need for one euploid embryo?

It depends on age (euploid rate) and how many embryos reach blastocyst. The model shows both pieces: a per-embryo euploid percentage and expected blast count. If you’re family-building over time, you may also consider the egg freezing success rate tool for strategy.

Does day-3 vs day-5 culture change results?

Culture strategy affects how many embryos reach testing/transfer. The euploid rate is largely age-related, but the number of testable/transferable embryos can differ. For transfer considerations, see embryo grade success rate.

Can male factor change euploid probability?

Severe sperm DNA fragmentation or very low counts may impact embryo development. Use the semen analysis & TMSC interpreter for context and discuss with your clinic.

How does this relate to IVF success rates?

Euploid embryos generally have higher implantation potential. For age-stratified clinical outcomes, compare with the IVF success rate by age calculator.

This calculator uses age-based euploid probability curves and an AMH-informed estimate of blastocyst yield to produce a planning-stage estimate. It’s intended for education and shared decision-making—please discuss your individual plan and protocol with your clinician.